noun

• (colloquial, uncountable) vomit.
  "2007, The Guardian, The Guardian Science blog, "The latest in the war on terror: the puke saber" the puke saber … pulses light over rapidly changing wavelengths, apparently inducing "disorientation, nausea and even vomiting""
• (colloquial, countable) A drug that induces vomiting.
  ""at 8 a.m. took a puke of vinum antimoniale; which operated very kindly; was very weak the remainder of the day.""
• (colloquial, countable) A worthless, despicable person.
• (US, slang, derogatory, countable) A person from Missouri.
  ""Pukes" and "suckers" had badly mauled the Saints, the first pummeling them from Missouri and the second from Illinois."

verb

• (colloquial, ambitransitive) To vomit; to throw up; to eject from the stomach.
  "Unfortunately, he could not hold it long enough till the end of the ride, so he puked on the bus seat."
• (intransitive, finance, slang) To sell securities or investments at a loss, often under duress or pressure, in order to satisfy liquidity or margin requirements, or out of a desire to exit a deteriorating market.