adj

• (baseball) When a batter successfully reaches first base, or when a baserunner successfully advances to the next base or returns to the base he last occupied; not out.
  "The pitcher attempted to pick off the runner at first, but he was safe."
• (snooker, of an object ball) In a location that renders it difficult to pot.
• (used after a noun, often forming a compound) Not susceptible to a specified source of harm.
  "dishwasher-safe"
• (UK, slang) Great, cool, awesome, respectable; a term of approbation, often as interjection.
  "and you also forgot to mentioned^([sic]) the wheels man you know bmw playing / ragga jungle hip hop tunes / and on the mobile / yeah safe! / nice one / later"

noun

• (slang) A condom.
  "Condoms ARE available, on the underground market, at the outrageous price of ten dollars a piece! Now, I do not mind paying ten bucks for a good piece, as well as some peace of mind, but even the mere possession of these 'safes' is a disciplinary offense!"
• (dated) A ventilated or refrigerated chest or closet for securing provisions from noxious animals or insects.
  "The other room was a kitchen, with an open fireplace, a safe, a dresser and a tin sink, with a tap from the tank outside."
• (dated, colloquial) A safety bicycle.

verb

• (transitive) To make something safe.
  "“It just trails behind the pylon until I land, then Cramer removes it when he safes the rocket pods. No evidence of anything when I taxi back inside the compound.”"

name

• (European Union) Acronym of Security Action for Europe.
  "EU countries have in principle agreed on the proposals for a 150 billion euro ($168.3 billion) fund aimed at boosting Europe's defence, known as Security Action for Europe (SAFE), an EU diplomat said on Monday."