adj

• (figuratively, dated) Of people: having a tendency to oppose; obstinate, perverse, stubborn.
  "[…] harke Nature, heare deere Goddeſſe, ſuſpend thy purpoſe, if thou did'ſt intend to make this creature fruitful into her wombe, conuey ſterility, drie vp in hir the organs of increaſe, and from her derogate body neuer ſpring a babe to honour her, if ſhee muſt teeme, create her childe of ſpleene, that it may liue and bee a thourt diſuetur'd^([sic – meaning disnatured]) torment to her, […]"
• (figuratively, dated) Of situations or things: adverse, unfavourable, unlucky.

adv

• (obsolete) Across the direction of travel or length of; athwart, crosswise, obliquely, transversely.
  "With adverſe blaſt up-turns them from the South Notus and Afer black with thundrous Clouds From Serraliona; thwart of theſe as fierce Forth ruſh the Levant and the Ponent VVindes Eurus and Zephir with their lateral noiſe, Sirocco, and Libecchio."

prep

• (archaic or poetic) Across, athwart.

verb

• (transitive) To cause to fail; to frustrate, to prevent.
  "Our plans for a picnic were thwarted by the thunderstorm."
• (transitive, obsolete) To place (something) across (another thing); to position crosswise.
• (transitive, also figuratively, obsolete) To hinder or obstruct by placing (something) in the way of; to block, to impede, to oppose.
• (ambitransitive, obsolete) To move (something) across or counter to; to cross.
  "An arrow thwarts the air."