noun

• (uncountable) The action of vexing, annoying, or irritating someone or something; (countable) an instance of this.
  "[…] I mourne in my prayer, and make a noiſe, / For the voyce of the enemie, & for the vexation of the vvicked, becauſe they haue broght iniquitie vpon me, & furiouſly hate me."
• (uncountable) The action of vexing, annoying, or irritating someone or something; (countable) an instance of this.
  "And, gentle Puck, take this transformed ſcalpe, / From the heade of this Athenian ſvvaine [Nick Bottom]; / That hee, avvaking vvhen the other do, / May all to Athens backe againe repaire, / And thinke no more of this nights accidents, / But as the fearce vexation of a dreame."
• (uncountable) The action of vexing, annoying, or irritating someone or something; (countable) an instance of this.
• (uncountable) The state of being vexed, annoyed, or irritated; annoyance, irritation; also, disappointment, discontentment, unhappiness; (countable) an instance of this.
  ""Indeed you perplex me intolerably;" cried Cecilia, vvith ſome vexation, "VVhy, Sir, vvill you not be more explicit?""